SNPs and microsatellites serve as useful genetic markers for whole-genome analysis on linkage to monogenetic traits, or association to complex diseases, as well as for the identification of samples and profiling cell lines during experimental work. Besides these two types of markers, other signatures of genomes can be investigated like DNA methylation sites, panels of known disease-associated variants. Analysing those variants can be done in a high-throughput fashion applying array technologies, or at a lower scale via real-time PCR, pyrosequencing and capillary gel electrophoresis, respectively.