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Prof. Peter Nürnberg, Ph.D.

Prof. Peter Nürnberg, Ph.D.
Prof. Peter Nürnberg, Ph.D.

Cologne Center for Genomics (CCG)
University of Cologne
D-50931 Köln/Germany
Phone: +49 221 478-96801
Fax:     +49 221 478-96803

Curriculum Vitae

1981 Diploma in Biology, Humboldt-University Berlin
1981-1984 Ph.D. thesis (Dr. rer. nat.) in Biochemistry, Humboldt-University Berlin
1984-1987 Post-doc at the Central Institute of Molecular Biology, Berlin-Buch
1987-1989 Staff member, Institute of Medical Genetics, Charité, Berlin
1990 Visiting Research Investigator, AG Epplen, Max Planck Institute of Psychiatry, Martinsried/ Bavaria
1990-2000 Head of the Dept. of Molecular Genetics, Institute of Medical Genetics, Charité, Berlin
1997 Postdoctoral lecturing qualification (Habilitation) with papers on genomic repetitive elements and their application as markers in molecular genetics, Humboldt-University Berlin
1998-2004 Appointment to “Oberassistent” (C2) at the Institute of Medical Genetics, Charité, Berlin
2000-2004 Head of the Gene Mapping Center (GMC) at the Max Delbrück Center (MDC) for Molecular Medicine, Berlin-Buch
2004-2023 Professor (full) of Genomics, University of Cologne, Head of the Cologne Center for Genomics

Research Activities

Awards and Honors

Humboldt Award 1985

Research Activities

  • Projects in CMMC (Centre of Molecular Medicine Cologne)
  • SFB577
  • SFB680
  • collaborative research projects within the NGFN
  • Network activities in GeneSkin
  • coordinating and core center activities in EPICURE (FP6)

Memberships (Selection)

  • Coordinator of the National Genotyping Platform of the NGFN
  • President of the "Arbeitsgemeinschaft für Gendiagnostik e.V." (AGD)
  • CEO of the Atlas Biolabs GmbH

Selected Publications

Sayer JA, Otto EA, O'toole JF, Nürnberg G, Kennedy MA, Becker C, Hennies HC, Helou J, Attanasio M, Fausett BV, Utsch B, Khanna H, Liu Y, Drummond I, Kawakami I, Kusakabe T, Tsuda M, Ma L, Lee H, Larson RG, Allen SJ, Wilkinson CJ, Nigg EA, Shou C, Lillo C, Williams DS, Hoppe B, Kemper MJ, Neuhaus T, Parisi MA, Glass IA, Petry M, Kispert A, Gloy J, Ganner A, Walz G, Zhu X, Goldman D, Nürnberg P, Swaroop A, Leroux MR, and Hildebrandt F. The centrosomal protein nephrocystin-6 is mutated in Joubert syndrome and activates transcription factor ATF4. Nat. Genet. 2006, 38(6): 674-81.

Rohmann E, Brunner HG, Kayserili H, Uyguner O, Nurnberg G, Lew ED, Dobbie A, Eswarakumar VP, Uzumcu A, Ulubil-Emeroglu M, Leroy JG, Li Y, Becker C, Lehnerdt K, Cremers CW, Yuksel-Apak M, Nürnberg P, Kubisch C, Schlessinger J, van Bokhoven H, and Wollnik B. Mutations in different components of FGF signaling in LADD syndrome. Nat. Genet. 2006, 38: 414-7.

Franke A, Wollstein A, Teuber M, Wittig M, Lu T, Hoffmann K, Nürnberg P, Krawczak M, Schreiber S, and Hampe J. GENOMIZER:an integrated analysis system for genome-wide association data. Hum. Mutat. 2006, 27: 583-588.

Gödde R, Rohde K, Becker C, Toliat MR, Entz P, Suk A, Muller N, Sindern E, Haupts M, Schimrigk S, Nürnberg P, and Epplen JT. Association of the HLA region with multiple sclerosis as confirmed by a genome screen using >10,000 SNPs on DNA chips. J. Mol. Med. 2005, 83: 486-494.

Metherell LA, Chapple JP, Cooray S, David A, Becker C, Ruschendorf F, Naville D, Begeot M, Khoo B, Nürnberg P, Huebner A, Cheetham ME, and Clark AJ. Mutations in MRAP, encoding a new interacting partner of the ACTH receptor, cause familial glucocorticoid deficiency type 2. Nat. Genet. 2005, 37: 166-170.

Kulle B, Schirmer M, Toliat MR, Suk A, Becker C, Tzvetkov MV, Brockmoller J, Bickeboller H, Hasenfuss G, Nürnberg P, and Wojnowski L. Application of genomewide SNP arrays for detection of simulated susceptibility loci. Hum. Mutat. 2005, 25: 557-565.

Janecke AR, Thompson DA, Utermann G, Becker C, Hubner CA, Schmid E, McHenry CL, Nair AR, Ruschendorf F, Heckenlively J, Wissinger B, Nürnberg P, and Gal A. Mutations in RDH12 encoding a photoreceptor cell retinol dehydrogenase cause childhood-onsetsevere retinal dystrophy. Nat. Genet. 2004, 36: 850-4.

Knoblauch H, Bauerfeind A, Toliat MR, Becker C, Luganskaja T, Gunther UP, Rohde K, Schuster H, Junghans C, Luft FC, Nürnberg P, and Reich JG. Haplotypes and SNPs in 13 lipid-relevant genes explain most of the genetic variance in high-density lipoprotein and low-density lipoprotein cholesterol. Hum. Mol. Genet. 2004, 13: 993-1004.

Rutsch F, Ruf N, Vaingankar S, Toliat MR, Suk A, Hohne W, Schauer G, Lehmann M, Roscioli T, Schnabel D, Epplen JT, Knisely A, Superti-Furga A, McGill J, Filippone M, Sinaiko AR, Vallance H, Hinrichs B, Smith W, Ferre M, Terkeltaub R, and Nürnberg P. Mutations in ENPP1 are associated with 'idiopathic' infantile arterial calcification. Nat. Genet. 2003, 34: 379-381.

Nürnberg P, Thiele H, Chandler D, Hohne W, Cunningham ML, Ritter H, Leschik G, Uhlmann K, Mischung C, Harrop K, Goldblatt J, Borochowitz ZU, Kotzot D, Westermann F, Mundlos S, Braun HS, Laing N, and Tinschert S. Heterozygous mutations in ANKH, the human ortholog of the mouse progressive ankylosis gene, result in craniometaphyseal dysplasia. Nat. Genet. 2001, 28: 37-41.